黄永灿 副研究员，硕士生导师

Email：hycpku@hotmail.com

黄永灿，北京大学医学部副研究员，硕士生导师（外科学学术学位型），博士后合作导师，深圳北京大学香港科技大学医学中心骨病研究所副所长，深圳骨科疾病再生技术工程实验室主任，深圳市脊柱外科重点实验室副主任。先后入选深圳市海外高层次人才、深圳市高层次人才、福田英才（II类）和深圳市卫健委菁英人才等项目。

以第一或通讯作者（含共同）在Nature Reviews Rheumatology，Advanced Materials，Bioactive Materials，Advanced Science，Biomaterials，Journal of Materials Science & Technology和Spine Journal等等杂志发表论文99篇，获批专利10项。主持国家自然科学基金，广东省自然科学基金，深圳市科技创新委员会、深圳市发展和改革委员会、深圳市工信局等各级科研项目10余项。是国际华人骨科研究学会(ICMRS) Membership Committee委员和终身会员、深圳市医院管理者协会医工融合与创新医疗专业委员会副主任委员，是Engineering、Journal of Translational Medicine、Frontiers in Endocrinology、World Journal of Stem Cells、《中国修复重建外科杂志》和《手术电子杂志》等杂志的Section副主编、编委或青年编委。

代表性论文：

1. Cai RP, Xiang Z, Huang LJ, Huang ZY, Zhuo CJ, Liu K, Parolini O, Huang YC*. Immunoregulatory properties of the human acellular amniotic membrane for diabetic wound healing. iScience 2026; in press. 

2. Huang LJ, Lu YN, Chen K*, Guan Q, Huang CY, Qin Y, Zhang LC, Wang Z*, Zheng YF*, Huang YC*. Bridging research and application: biodegradable Zn-based alloys as next-generation orthopedic implants. Advanced Materials 2026;38(4): e13733.

3. Chen K, Li P, Guan Q, Gu XN*, Zhao L, Huang LJ, Huang CY, Qin Y, Yu CH, Zhang T, Huang YC*, Zheng YF*. Biodegradable zinc-based alloys for guided bone regeneration membranes: feasibility, current status and future prospects. Advanced Science 2025; e06513.

4. Chen K, Gao S, Gu XN*, Zhao L, Lu YN, Bai JW, Huang LJ, Yang HT, Qin Y, Zhou F, Huang YC*, Lv Y*, Zheng YF*. Monoplasmatic rare-earth Ge phases induced Zn-Ge micro-galvanic cells regulate the biodegradation behavior and osteointegration activity of zinc-based osteoimplants. Biomaterials. 2025; 321:123343.

5. Bi XW, Mao ZN, Zhang YL, Chen L, Yang K, Zheng R, Guan J, Liu ZH, Yu BS, Huang YC*, Shu X*, Zheng YF*. Endogenous dual-responsive and self-adaptive silk fibroin-based scaffold with enhancement of immunomodulation for skull regeneration. Biomaterials, 2025;320:123261.

6. Qin Y, Yu CH, Wang P, Yang HT, Liu AB, Wang SH, Shen ZQ, Ma SJ, Huang YC*, Yu BS*, Wen P*, Zheng YF*. Design and development of the additively manufactured Zn-Li scaffolds for posterolateral lumbar fusion. Journal of Materials Science & Technology 2025; 215:180-191. 

7. Ma C, Xin Q, Wei YF, Li Z, Zhang HL, Li H, Yu FL, Pu YN*, Huang YC*, Ren YX*. Amelioration of ligamentum flavum hypertrophy using umbilical cord mesenchymal stromal cell-derived extracellular vesicles. Bioactive Materials 2023; 19: 139-154. 

8. Chen JX, Li YH, Wen J, Li Z, Yu BS*, Huang YC*. Annular defects impair the mechanical stability of the intervertebral disc. Global Spine Journal 2023; 13(3):724-729. 

9. Yang F#, Liu WJ#, Huang YC#, Yang SH, Shao ZW, Cai XY, Xiong LM. Regulated cell death: implications for intervertebral disc degeneration and therapy. Journal of Orthopaedic Translation 2022. 37: 163-172. 

10. Li YH, Wu HL, Li Zhen, Li BB, Chen D, Ye FH*, Yu BS*, Huang YC*. Species variation in the cartilaginous endplate of the lumbar intervertebral disc. JOR Spine 2022; e1218.

11. Liu Y, Wang DL, Huang YC*, Wang TB*, Zeng H*. Hydrogen inhibits the osteoclastogenesis of mouse bone marrow mononuclear cells. Materials Science and Engineering C: Materials for Biological Applications 2020; 110: 110640.

12. Huang YZ, Wu CG, Xie HQ, Silini A, Parolini O, Liu K, Li ZY, Deng L*, Huang YC*. Strontium promotes the proliferation and osteogenic differentiation of human placental decidual basalis and bone marrow derived MSCs in a dose-dependent manner. Stem Cells International 2019; 4242178. 

13. Xue SL, Liu K, Parolini O, Wang Y, Deng L, Huang YC*. Human acellular amniotic membrane implantation for lower third nasal reconstruction: a promising therapy to promote wound healing. Burns & Trauma, 2018; 6:34.

14. Huang YC#, Xiao J#, Leung V, Lu WW, Hu Y, Luk KD. Lumbar intervertebral disc allograft transplantation: the revascularisation pattern. European Spine Journal 2018; 27: 728-36. 

15. Huang YC#, Xiao J#, Lu WW, Leung V, Hu Y, Luk KD. Lumbar intervertebral disc allograft transplantation: long-term mobility and impact on the adjacent segments. European Spine Journal 2017, 26: 799-805. 

16. Huang YC#, Xiao J#, Leung V, Lu WW, Hu Y, Luk KD. Lumbar intervertebral disc allograft transplantation: healing and remodeling of the bony structure. European Cells & Materials 2016; 36:216-227.

17. Xiao J#, Huang YC#, Lam SK, Luk KD. Surgical techniques for lumbar intervertebral disc transplantation in a goat model. European Spine Journal 2015; 24: 1951-8.

18. Huang YC, Urban J, Luk KD. Intervertebral disc regeneration: do nutrients lead the way? Nature Reviews Rheumatology 2014; 10: 561-66.

主持科研项目：

1. 广东省基础与应用基础研究基金委员会, 面上项目, 2023A1515220095, 载MSCs丝蛋白微球复合可注射GelMA水凝胶延缓同种异体椎间盘移植后退变的实验研究, 2023/11-2026/10, 10万元, 在研, 主持

2. 深圳市战略性新兴产业和未来产业发展专项，深圳市骨科疾病再生技术工程实验室提升项目，2022/04-2026/03，500万，在研，主持；

3. 深圳市科技创新委员会国际合作项目，GJHZ20210705142543019, 载镁脱细胞羊膜的构建及其促进糖尿病足溃疡愈合的实验研究，2022/07-2025/07，50万，已结题，主持；

4. 广东省基础与应用基础研究基金面上项目，2021A1515220086，经有机锶涂层修饰的PEEK椎间融合器促进椎间骨融合的实验研究，2021/11-2024/10，10万，已结题，主持；